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SMILES: C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCC(O)CC3)C2=O)c(C)n1

InChI Key: InChIKey=AZBQFBWFMZCYJD-FUESJGSZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200822   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))		BDBM200822
PNG
(8-hydroxy-2-[2-methyl-6-((2s,3'r)-2-methyl-[1,...)
Show SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCC(O)CC3)C2=O)c(C)n1 |r,wU:6.6,wD:1.0,(5.66,-3.46,;6.99,-2.69,;8.46,-3.17,;9.36,-1.92,;8.46,-.68,;6.99,-1.15,;5.66,-.38,;5.66,1.16,;4.2,1.63,;3.29,.38,;4.2,-.86,;1.75,.38,;.98,-.95,;-.56,-.95,;-1.33,.38,;-2.99,.38,;-3.9,-.86,;-5.36,-.39,;-5.36,1.15,;-5.36,2.69,;-6.7,3.46,;-8.03,2.69,;-9.36,3.46,;-8.03,1.15,;-6.7,.38,;-3.9,1.63,;-3.13,2.96,;-.56,1.72,;-1.33,3.05,;.98,1.72,)|
Show InChI InChI=1S/C24H36N4O2/c1-17-4-3-13-27(17)19-9-14-26(16-19)22-6-5-21(18(2)25-22)28-15-12-24(23(28)30)10-7-20(29)8-11-24/h5-6,17,19-20,29H,3-4,7-16H2,1-2H3/t17-,19+,20?,24?/m0/s1
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
 267n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...

US Patent US9533995 (2017)


BindingDB Entry DOI: 10.7270/Q25H7DFS
More data for this
Ligand-Target Pair