BDBM200829 2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)-pyridin-3-yl]-2,9-diaza-spiro[5.5]undecan-1-one hydrochloride::US9533995, 9
SMILES: C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCCC3(CCNCC3)C2=O)c(C)n1
InChI Key: InChIKey=LZWCHVKJGNMAEK-AZUAARDMSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine receptor H3 (Macaca mulatta (Rhesus macaque)) | BDBM200829 (2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 38.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi US Patent | Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme... | US Patent US9533995 (2017) BindingDB Entry DOI: 10.7270/Q25H7DFS | |||||||||||
More data for this Ligand-Target Pair |