BDBM200833 2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)-pyridin-2-yl]-8-oxa-2-aza-spiro[4.5]decan-1-one::US9533995, 13

SMILES: C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(nc1)N1CCC2(CCOCC2)C1=O

InChI Key: InChIKey=FGMTUSMVHGDCCU-HKUYNNGSSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM200833 (2-[5-((2s,3's)-2-methyl-[1,3']bipyrrolidin...) Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(nc1)N1CCC2(CCOCC2)C1=O |r| Show InChI InChI=1S/C22H32N4O2/c1-17-3-2-10-25(17)19-6-11-24(16-19)18-4-5-20(23-15-18)26-12-7-22(21(26)27)8-13-28-14-9-22/h4-5,15,17,19H,2-3,6-14,16H2,1H3/t17-,19-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9533995 (2017) BindingDB Entry DOI: 10.7270/Q25H7DFS
					More data for this Ligand-Target Pair