null

SMILES: FC(F)(F)Oc1cc(CN2C(=O)CS(=O)(=O)c3cccnc23)ccc1Cl

InChI Key: InChIKey=ITMXBFPPKCNHHZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200855 (US9533999, i-12) Show SMILES FC(F)(F)Oc1cc(CN2C(=O)CS(=O)(=O)c3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2O4S/c16-10-4-3-9(6-11(10)25-15(17,18)19)7-21-13(22)8-26(23,24)12-2-1-5-20-14(12)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair