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BDBM200905 US9533999, i-39

SMILES: Fc1ccc(CN2c3sccc3S(=O)(=O)CC2=O)cc1OC(F)(F)F

InChI Key:

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200905   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM200905
PNG
(US9533999, i-39)
Show SMILES Fc1ccc(CN2c3sccc3S(=O)(=O)CC2=O)cc1OC(F)(F)F
PDB

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PC cid
PC sid
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US Patent
n/an/a 39n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...


US Patent US9533999 (2017)


BindingDB Entry DOI: 10.7270/Q21V5C4S
More data for this
Ligand-Target Pair