BDBM200940 US9233946, 39

SMILES: Cc1c(sc2ccccc12)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key: InChIKey=QTKZILXILDWMNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) (Homo sapiens (Human))	BDBM200940 (US9233946, 39) Show SMILES Cc1c(sc2ccccc12)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C16H13N5O2S2/c1-10-13-7-2-3-8-14(13)24-16(10)25(22,23)19-12-6-4-5-11(9-12)15-17-20-21-18-15/h2-9,19H,1H3,(H,17,18,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...				US Patent US9233946 (2016) BindingDB Entry DOI: 10.7270/Q2V123KB
					More data for this Ligand-Target Pair