BindingDB logo
myBDB logout

null

SMILES: CC(N1c2nc(C)sc2SCC1=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=BEWUIYPVYZKESU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200973   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))		BDBM200973
PNG
(US9533999, ii-23)
Show SMILES CC(N1c2nc(C)sc2SCC1=O)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C15H13F3N2OS2/c1-8(10-4-3-5-11(6-10)15(16,17)18)20-12(21)7-22-14-13(20)19-9(2)23-14/h3-6,8H,7H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 67n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...

US Patent US9533999 (2017)


BindingDB Entry DOI: 10.7270/Q21V5C4S
More data for this
Ligand-Target Pair