BindingDB logo
myBDB logout

null

SMILES: Cc1cc(Oc2nccc3ccccc23)ccc1-c1c(C)n[nH]c(=O)c1C

InChI Key: InChIKey=XOYZFMWRWJBPAA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200985   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(1A) dopamine receptor


(Homo sapiens (Human))		BDBM200985
PNG
(5-[4-(isoquinolin-1-yloxy)-2-methylphenyl]- 4,6-di...)
Show SMILES Cc1cc(Oc2nccc3ccccc23)ccc1-c1c(C)n[nH]c(=O)c1C |(.67,3.47,;.67,1.93,;-.67,1.15,;-.67,-.38,;-2,-1.15,;-2,-2.69,;-.67,-3.47,;-.67,-5,;-2,-5.78,;-3.33,-5,;-4.67,-5.78,;-6,-5,;-6,-3.47,;-4.67,-2.69,;-3.33,-3.47,;.67,-1.15,;2,-.38,;2,1.15,;3.33,1.93,;4.67,1.15,;4.67,-.38,;6,1.93,;6,3.47,;4.67,4.23,;4.67,5.78,;3.33,3.47,;2,4.23,)|
Show InChI InChI=1S/C22H19N3O2/c1-13-12-17(27-22-19-7-5-4-6-16(19)10-11-23-22)8-9-18(13)20-14(2)21(26)25-24-15(20)3/h4-12H,1-3H3,(H,25,26)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 7.80n/an/an/an/an/an/a7.4n/a



Pfizer Inc.

US Patent


Assay Description
The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...

US Patent US9540352 (2017)


BindingDB Entry DOI: 10.7270/Q2X34VND
More data for this
Ligand-Target Pair