BDBM201002 US9233946, 101

SMILES: Fc1ccc(-c2ccc(s2)S(=O)(=O)Nc2cccc(c2)-c2nnn[nH]2)c(F)c1

InChI Key: InChIKey=SWJBDTDOOUUIAP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM201002 (US9233946, 101) Show SMILES Fc1ccc(-c2ccc(s2)S(=O)(=O)Nc2cccc(c2)-c2nnn[nH]2)c(F)c1 Show InChI InChI=1S/C17H11F2N5O2S2/c18-11-4-5-13(14(19)9-11)15-6-7-16(27-15)28(25,26)22-12-3-1-2-10(8-12)17-20-23-24-21-17/h1-9,22H,(H,20,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...				US Patent US9233946 (2016) BindingDB Entry DOI: 10.7270/Q2V123KB
					More data for this Ligand-Target Pair