BDBM201003 US9233946, 102

SMILES: Fc1ccc(cc1Cl)-c1ccc(s1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1

InChI Key: InChIKey=HPAPOOVVQHAFPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) (Homo sapiens (Human))	BDBM201003 (US9233946, 102) Show SMILES Fc1ccc(cc1Cl)-c1ccc(s1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1 Show InChI InChI=1S/C17H11ClFN5O2S2/c18-13-9-10(4-5-14(13)19)15-6-7-16(27-15)28(25,26)22-12-3-1-2-11(8-12)17-20-23-24-21-17/h1-9,22H,(H,20,21,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
KANCERA AB US Patent					Assay Description Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...				US Patent US9233946 (2016) BindingDB Entry DOI: 10.7270/Q2V123KB
					More data for this Ligand-Target Pair