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BDBM201044 US9233953, 5

SMILES: Fc1cccc(c1)[C@@H]1CN(CCN1C(=O)C1CCS(=O)(=O)CC1)c1ncc(cn1)C(F)(F)F

InChI Key: InChIKey=MZCMJTPIGBNWLZ-LGWFVXIRNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201044   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM201044
PNG
(US9233953, 5)
Show SMILES Fc1cccc(c1)[C@@H]1CN(CCN1C(=O)C1CCS(=O)(=O)CC1)c1ncc(cn1)C(F)(F)F |r|
Show InChI InChI=1/C21H22F4N4O3S/c22-17-3-1-2-15(10-17)18-13-28(20-26-11-16(12-27-20)21(23,24)25)6-7-29(18)19(30)14-4-8-33(31,32)9-5-14/h1-3,10-12,14,18H,4-9,13H2/t18-/s2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...


US Patent US9233953 (2016)


BindingDB Entry DOI: 10.7270/Q2Q81BVM
More data for this
Ligand-Target Pair