BDBM201052 US9233953, 13
SMILES: Fc1ccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2ncc(cn2)C(F)(F)F)c(F)c1
InChI Key: InChIKey=KHNIIFGKLRLLQH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycine transporter 1 (Homo sapiens (Human)) | BDBM201052 (US9233953, 13) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel... | US Patent US9233953 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BVM | |||||||||||
More data for this Ligand-Target Pair |