BDBM201070 US9233953, 31

SMILES: Fc1ccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2cc(on2)C(F)(F)F)c(F)c1

InChI Key: InChIKey=CDDIBAYPGHOKBS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM201070 (US9233953, 31) Show SMILES Fc1ccc(C2CN(CCN2C(=O)C2CCS(=O)(=O)CC2)c2cc(on2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C20H20F5N3O4S/c21-13-1-2-14(15(22)9-13)16-11-27(18-10-17(32-26-18)20(23,24)25)5-6-28(16)19(29)12-3-7-33(30,31)8-4-12/h1-2,9-10,12,16H,3-8,11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...				US Patent US9233953 (2016) BindingDB Entry DOI: 10.7270/Q2Q81BVM
					More data for this Ligand-Target Pair