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SMILES: Fc1ccccc1C1CN(CCN1C(=O)C1CCS(=O)(=O)CC1)c1cnc(cn1)C1CC1

InChI Key: InChIKey=SJPMLKGPTMFPNP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201120   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM201120
PNG
(US9233953, 81)
Show SMILES Fc1ccccc1C1CN(CCN1C(=O)C1CCS(=O)(=O)CC1)c1cnc(cn1)C1CC1
Show InChI InChI=1S/C23H27FN4O3S/c24-19-4-2-1-3-18(19)21-15-27(22-14-25-20(13-26-22)16-5-6-16)9-10-28(21)23(29)17-7-11-32(30,31)12-8-17/h1-4,13-14,16-17,21H,5-12,15H2
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PC cid
PC sid
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US Patent
n/an/a 8n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...

US Patent US9233953 (2016)


BindingDB Entry DOI: 10.7270/Q2Q81BVM
More data for this
Ligand-Target Pair