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SMILES: Cc1cnc(cn1)N1CCN(C(C1)c1ccc(F)s1)C(=O)C1CCS(=O)(=O)CC1

InChI Key: InChIKey=LSFCOUKXNFKYAL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM201126
PNG
(US9233953, 87)
Show SMILES Cc1cnc(cn1)N1CCN(C(C1)c1ccc(F)s1)C(=O)C1CCS(=O)(=O)CC1
Show InChI InChI=1S/C19H23FN4O3S2/c1-13-10-22-18(11-21-13)23-6-7-24(15(12-23)16-2-3-17(20)28-16)19(25)14-4-8-29(26,27)9-5-14/h2-3,10-11,14-15H,4-9,12H2,1H3
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PC cid
PC sid
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US Patent
n/an/a 10n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...

US Patent US9233953 (2016)


BindingDB Entry DOI: 10.7270/Q2Q81BVM
More data for this
Ligand-Target Pair