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BDBM201163 US9233953, 123

SMILES: Clc1ccc(cc1)N1CCN(C(C1)c1cccs1)C(=O)C1CCS(=O)(=O)CC1

InChI Key: InChIKey=NIESQQKYNXGNFU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201163   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM201163
PNG
(US9233953, 123)
Show SMILES Clc1ccc(cc1)N1CCN(C(C1)c1cccs1)C(=O)C1CCS(=O)(=O)CC1
Show InChI InChI=1/C20H23ClN2O3S2/c21-16-3-5-17(6-4-16)22-9-10-23(18(14-22)19-2-1-11-27-19)20(24)15-7-12-28(25,26)13-8-15/h1-6,11,15,18H,7-10,12-14H2
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Cells expressing either endogenously the GlyT1 transporter like JAR cells (human placental choriocarcinoma cells; e.g. WO 2008/002583) or SK-N-MC cel...


US Patent US9233953 (2016)


BindingDB Entry DOI: 10.7270/Q2Q81BVM
More data for this
Ligand-Target Pair