BDBM20148 5-(4-chlorophenyl)-2-(3-methoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 9

SMILES: COc1cccc(c1)C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(Cl)cc1

InChI Key: InChIKey=IJPQKGYDDLFFKO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM20148 (5-(4-chlorophenyl)-2-(3-methoxyphenyl)-3-[(2,4,6-t...) Show SMILES COc1cccc(c1)C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(Cl)cc1 |c:11| Show InChI InChI=1S/C22H14ClF3N2O2S/c1-30-16-4-2-3-13(9-16)22-28(21(29)19-17(25)10-15(24)11-18(19)26)27-20(31-22)12-5-7-14(23)8-6-12/h2-11,22H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	7.2	37
GNF					Assay Description FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...				J Med Chem 50: 4255-9 (2007) Article DOI: 10.1021/jm070453f BindingDB Entry DOI: 10.7270/Q2BK19N6
					More data for this Ligand-Target Pair