BDBM201508 US9187424, 275

SMILES: FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccncc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F

InChI Key: InChIKey=RZAKRVONXKTCPJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 201508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201508 (US9187424, 275) Show SMILES FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccncc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |c:11| Show InChI InChI=1S/C29H23F8N3O4/c30-26(31)44-21-6-2-17(3-7-21)22-16-27(29(35,36)37,19-4-8-20(9-5-19)43-15-1-12-28(32,33)34)40-25(42)23(22)39-24(41)18-10-13-38-14-11-18/h2-11,13-14,26H,1,12,15-16H2,(H,39,41)(H,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
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