BDBM20151 5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2-fluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 17

SMILES: COc1cccc(C2SC(=NN2C(=O)c2ccccc2F)c2ccc(Cl)cc2)c1OC

InChI Key: InChIKey=SSHNBLVLMIFHDU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM20151 (5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2-f...) Show SMILES COc1cccc(C2SC(=NN2C(=O)c2ccccc2F)c2ccc(Cl)cc2)c1OC |c:9| Show InChI InChI=1S/C23H18ClFN2O3S/c1-29-19-9-5-7-17(20(19)30-2)23-27(22(28)16-6-3-4-8-18(16)25)26-21(31-23)14-10-12-15(24)13-11-14/h3-13,23H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a
GNF					Assay Description FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...				J Med Chem 50: 4255-9 (2007) Article DOI: 10.1021/jm070453f BindingDB Entry DOI: 10.7270/Q2BK19N6
					More data for this Ligand-Target Pair