null
SMILES: COc1ccc(CN(CCCOc2cccc(CC(N)=O)c2)CC(c2ccccc2)c2ccccc2)c(F)c1
InChI Key: InChIKey=DIASBTZRVLJKDB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM20170 (2-(3-{3-[(2,2-diphenylethyl)[(2-fluoro-4-methoxyph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | 7.5 | 22 |
GlaxoSmithKline | Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding... | J Med Chem 45: 1963-6 (2002) Article DOI: 10.1021/jm0255116 BindingDB Entry DOI: 10.7270/Q2319T5G | |||||||||||
More data for this Ligand-Target Pair |