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BDBM20171 2-(3-{3-[(2,2-diphenylethyl)({[3-(trifluoromethyl)phenyl]methyl})amino]propoxy}phenyl)acetamide::Tertiary amine, 9

SMILES: NC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2)C(F)(F)F)c1

InChI Key: InChIKey=PVSVRPXIFWFGJY-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20171   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM20171
PNG
(2-(3-{3-[(2,2-diphenylethyl)({[3-(trifluoromethyl)...)
Show SMILES NC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2)C(F)(F)F)c1
Show InChI InChI=1S/C33H33F3N2O2/c34-33(35,36)29-16-7-11-26(20-29)23-38(18-9-19-40-30-17-8-10-25(21-30)22-32(37)39)24-31(27-12-3-1-4-13-27)28-14-5-2-6-15-28/h1-8,10-17,20-21,31H,9,18-19,22-24H2,(H2,37,39)
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Similars
Article
PubMed
n/an/an/an/a 85n/an/a7.522



GlaxoSmithKline



Assay Description
The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...

J Med Chem 45: 1963-6 (2002)


Article DOI: 10.1021/jm0255116
BindingDB Entry DOI: 10.7270/Q2319T5G
More data for this
Ligand-Target Pair