BDBM202112 US9233983, D-4

SMILES: CN1CCC(CC1)c1ccc(cc1)-c1cc2c(ncnc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(ccc2c1=O)C1CC1

InChI Key: InChIKey=MSMBHKRWMAYJOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM202112 (US9233983, D-4) Show SMILES CN1CCC(CC1)c1ccc(cc1)-c1cc2c(ncnc2[nH]1)-c1cccc(c1CO)-n1ccc2cc(ccc2c1=O)C1CC1 Show InChI InChI=1S/C37H35N5O2/c1-41-16-13-25(14-17-41)23-7-9-26(10-8-23)33-20-31-35(38-22-39-36(31)40-33)30-3-2-4-34(32(30)21-43)42-18-15-28-19-27(24-5-6-24)11-12-29(28)37(42)44/h2-4,7-12,15,18-20,22,24-25,43H,5-6,13-14,16-17,21H2,1H3,(H,38,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ADVINUS THERAPEUTICS LIMITED US Patent					Assay Description The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...				US Patent US9233983 (2016) BindingDB Entry DOI: 10.7270/Q22J69PQ
					More data for this Ligand-Target Pair