BDBM202124 US9233983, F-1

SMILES: OCc1c(cccc1-c1ccnc2[nH]c(cc12)-c1cnn(c1)C1COC1)N1CCOc2cc(ccc2C1=O)C1CC1

InChI Key: InChIKey=VCNBLMWKOHUIOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM202124 (US9233983, F-1) Show SMILES OCc1c(cccc1-c1ccnc2[nH]c(cc12)-c1cnn(c1)C1COC1)N1CCOc2cc(ccc2C1=O)C1CC1 Show InChI InChI=1S/C32H29N5O4/c38-16-27-23(24-8-9-33-31-26(24)13-28(35-31)21-14-34-37(15-21)22-17-40-18-22)2-1-3-29(27)36-10-11-41-30-12-20(19-4-5-19)6-7-25(30)32(36)39/h1-3,6-9,12-15,19,22,38H,4-5,10-11,16-18H2,(H,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ADVINUS THERAPEUTICS LIMITED US Patent					Assay Description The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...				US Patent US9233983 (2016) BindingDB Entry DOI: 10.7270/Q22J69PQ
					More data for this Ligand-Target Pair