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SMILES: Cn1cnc(c1)S(=O)(=O)NCCOc1cccc(c1)C(CN)Cc1cc(F)cc(F)c1

InChI Key: InChIKey=OUJINOAVBIQSRB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202248   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM202248
PNG
(US9238619, 11)
Show SMILES Cn1cnc(c1)S(=O)(=O)NCCOc1cccc(c1)C(CN)Cc1cc(F)cc(F)c1
Show InChI InChI=1S/C21H24F2N4O3S/c1-27-13-21(25-14-27)31(28,29)26-5-6-30-20-4-2-3-16(10-20)17(12-24)7-15-8-18(22)11-19(23)9-15/h2-4,8-11,13-14,17,26H,5-7,12,24H2,1H3
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US Patent
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...

US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair