BDBM202283 US9238619, 37

SMILES: Cn1cc(cn1)S(=O)(=O)NCc1cccc(c1)C(CN1CCC1)Cc1ccccc1

InChI Key: InChIKey=SPVOBSRIRDTEGQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM202283 (US9238619, 37) Show SMILES Cn1cc(cn1)S(=O)(=O)NCc1cccc(c1)C(CN1CCC1)Cc1ccccc1 Show InChI InChI=1S/C23H28N4O2S/c1-26-18-23(16-24-26)30(28,29)25-15-20-9-5-10-21(14-20)22(17-27-11-6-12-27)13-19-7-3-2-4-8-19/h2-5,7-10,14,16,18,22,25H,6,11-13,15,17H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...				US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F
					More data for this Ligand-Target Pair