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SMILES: CN(CCOc1cc(ccc1F)C1(Cc2ccccc2)CN(C)C1)S(=O)(=O)c1cn(C)cn1

InChI Key: InChIKey=ZLOGEPWQDUFPRX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202322   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 1


(Homo sapiens (Human))		BDBM202322
PNG
(US9238619, 53)
Show SMILES CN(CCOc1cc(ccc1F)C1(Cc2ccccc2)CN(C)C1)S(=O)(=O)c1cn(C)cn1
Show InChI InChI=1S/C24H29FN4O3S/c1-27-15-23(26-18-27)33(30,31)29(3)11-12-32-22-13-20(9-10-21(22)25)24(16-28(2)17-24)14-19-7-5-4-6-8-19/h4-10,13,15,18H,11-12,14,16-17H2,1-3H3
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US Patent
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...

US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair