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BDBM202350 US9238619, 69

SMILES: CN1CCC(Cc2ccccc2)(C1)c1cccc(CNS(=O)(=O)c2cnn(C)c2)c1

InChI Key: InChIKey=MXWWAZZLJCLTPJ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202350   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM202350
PNG
(US9238619, 69)
Show SMILES CN1CCC(Cc2ccccc2)(C1)c1cccc(CNS(=O)(=O)c2cnn(C)c2)c1
Show InChI InChI=1/C23H28N4O2S/c1-26-12-11-23(18-26,14-19-7-4-3-5-8-19)21-10-6-9-20(13-21)15-25-30(28,29)22-16-24-27(2)17-22/h3-10,13,16-17,25H,11-12,14-15,18H2,1-2H3
KEGG

UniProtKB/SwissProt

DrugBank
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PC cid
PC sid
UniChem
US Patent
<1n/an/an/an/an/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171...


US Patent US9238619 (2016)


BindingDB Entry DOI: 10.7270/Q2XS5T6F
More data for this
Ligand-Target Pair