BDBM202406 US9238644, 13

SMILES: Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(CC3)C(N)=O)n2)cn1

InChI Key: InChIKey=KUZRTSMZHWGUIV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 202406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM202406 (US9238644, 13) Show SMILES Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(CC3)C(N)=O)n2)cn1 Show InChI InChI=1S/C20H21ClN6O/c1-27-12-14(10-24-27)25-19-23-11-16(21)17(26-19)7-6-13-4-2-3-5-15(13)20(8-9-20)18(22)28/h2-5,10-12H,6-9H2,1H3,(H2,22,28)(H,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	257	n/a	n/a	n/a	n/a	7.2	37
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description Adult human umbilical vein endothelial cells (HUVEC) (Cat# CC-2519, Lonza) were seeded into clear-bottom, TC treated 12 well plates (Cat #665180, G...				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM202406 (US9238644, 13) Show SMILES Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(CC3)C(N)=O)n2)cn1 Show InChI InChI=1S/C20H21ClN6O/c1-27-12-14(10-24-27)25-19-23-11-16(21)17(26-19)7-6-13-4-2-3-5-15(13)20(8-9-20)18(22)28/h2-5,10-12H,6-9H2,1H3,(H2,22,28)(H,23,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.2	37
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM202406 (US9238644, 13) Show SMILES Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C3(CC3)C(N)=O)n2)cn1 Show InChI InChI=1S/C20H21ClN6O/c1-27-12-14(10-24-27)25-19-23-11-16(21)17(26-19)7-6-13-4-2-3-5-15(13)20(8-9-20)18(22)28/h2-5,10-12H,6-9H2,1H3,(H2,22,28)(H,23,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	n/a
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair