BDBM202475 US9238644, 76

SMILES: NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cnn(CCO)c2)ncc1Cl

InChI Key: InChIKey=IHZXMSITVWOAII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM202475 (US9238644, 76) Show SMILES NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2cnn(CCO)c2)ncc1Cl Show InChI InChI=1S/C21H23ClN6O2/c22-17-12-24-20(26-15-11-25-28(13-15)9-10-29)27-18(17)6-5-14-3-1-2-4-16(14)21(7-8-21)19(23)30/h1-4,11-13,29H,5-10H2,(H2,23,30)(H,24,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	n/a
CANCER THERAPEUTICS CRC PTY LIMITED US Patent					Assay Description A biotin labelled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)....				US Patent US9238644 (2016) BindingDB Entry DOI: 10.7270/Q2JM28FP
					More data for this Ligand-Target Pair