BDBM203448 US9242981, 147

SMILES: CCn1cc(cn1)-c1n[nH]c2CCN(Cc12)C(=O)NC1CN(C)CC1c1ccccc1C

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 203448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Mus musculus (Mouse))	BDBM203448 (US9242981, 147) Show SMILES CCn1cc(cn1)-c1n[nH]c2CCN(Cc12)C(=O)NC1CN(C)CC1c1ccccc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 14 &#...				US Patent US9242981 (2016) BindingDB Entry DOI: 10.7270/Q2GM864G
					More data for this Ligand-Target Pair