BDBM204785 US9243002, 83::US9243002, 86

SMILES: CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1

InChI Key: InChIKey=DOYHTBMIICNEKT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 204785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM204785 (US9243002, 83 | US9243002, 86) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H24FN5O4S/c1-37-34(41)31-25-15-24(28(39(2)45(3,42)43)17-30(25)44-33(31)20-7-10-22(35)11-8-20)26-12-9-19-13-14-40-27-6-4-5-21(18-36)23(27)16-29(40)32(19)38-26/h4-17H,1-3H3,(H,37,41)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.49	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM204785 (US9243002, 83 | US9243002, 86) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H24FN5O4S/c1-37-34(41)31-25-15-24(28(39(2)45(3,42)43)17-30(25)44-33(31)20-7-10-22(35)11-8-20)26-12-9-19-13-14-40-27-6-4-5-21(18-36)23(27)16-29(40)32(19)38-26/h4-17H,1-3H3,(H,37,41)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.05	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C Virus (Virus))	BDBM204785 (US9243002, 83 | US9243002, 86) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H24FN5O4S/c1-37-34(41)31-25-15-24(28(39(2)45(3,42)43)17-30(25)44-33(31)20-7-10-22(35)11-8-20)26-12-9-19-13-14-40-27-6-4-5-21(18-36)23(27)16-29(40)32(19)38-26/h4-17H,1-3H3,(H,37,41)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.44	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM204785 (US9243002, 83 | US9243002, 86) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ccn3c4cccc(C#N)c4cc3c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C34H24FN5O4S/c1-37-34(41)31-25-15-24(28(39(2)45(3,42)43)17-30(25)44-33(31)20-7-10-22(35)11-8-20)26-12-9-19-13-14-40-27-6-4-5-21(18-36)23(27)16-29(40)32(19)38-26/h4-17H,1-3H3,(H,37,41)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.91	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description To initiate an assay, replicon cells were plated in the presence of a dilution series of test compound in the absence of G418. Typically, the assays ...				US Patent US9243002 (2016) BindingDB Entry DOI: 10.7270/Q2P55MBC
					More data for this Ligand-Target Pair