BDBM204923 phosphonoacetohydroxamate (PhAH)

SMILES: ONC(=O)CP(O)(O)=O

InChI Key: InChIKey=LDKRAXXVBWHMRH-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 204923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
hENO2 human recombinant Enolase (Homo sapiens (Human))	BDBM204923 (phosphonoacetohydroxamate (PhAH)) Show SMILES ONC(=O)CP(O)(O)=O Show InChI InChI=1S/C2H6NO5P/c4-2(3-5)1-9(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	62.3	n/a	n/a	n/a	n/a	7.4	n/a
University of Texas MD Anderson Cancer Center					Assay Description Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...				Nat Chem Biol 12: 1053-1058 (2016) Article DOI: 10.1038/nchembio.2195 BindingDB Entry DOI: 10.7270/Q28W3C33
					More data for this Ligand-Target Pair				3D Structure (crystal)
Enolase 1 (ENO1) (Homo sapiens (Human))	BDBM204923 (phosphonoacetohydroxamate (PhAH)) Show SMILES ONC(=O)CP(O)(O)=O Show InChI InChI=1S/C2H6NO5P/c4-2(3-5)1-9(6,7)8/h5H,1H2,(H,3,4)(H2,6,7,8)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	53.2	n/a	n/a	n/a	n/a	7.4	n/a
University of Texas MD Anderson Cancer Center					Assay Description Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...				Nat Chem Biol 12: 1053-1058 (2016) Article DOI: 10.1038/nchembio.2195 BindingDB Entry DOI: 10.7270/Q28W3C33
					More data for this Ligand-Target Pair