BDBM205626 US9255090, 95

SMILES: COc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)C1CC1c1ccccc1C(F)(F)F

InChI Key: InChIKey=LPIIMLVCDPPYPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM205626 (US9255090, 95) Show SMILES COc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)C1CC1c1ccccc1C(F)(F)F Show InChI InChI=1S/C29H25F4NO4/c1-38-26-9-6-16(13-27(35)36)12-21(26)17-7-8-25(30)19-10-11-34(15-23(17)19)28(37)22-14-20(22)18-4-2-3-5-24(18)29(31,32)33/h2-9,12,20,22H,10-11,13-15H2,1H3,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair