BDBM205727 US9255090, 196

SMILES: OC(=O)Cc1ccc(OCC2CC2)c(c1)-c1ccc(F)c2CCN(Cc12)C(=O)OCc1ccccc1

InChI Key: InChIKey=KQTNLSLHCRIBDU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM205727 (US9255090, 196) Show SMILES OC(=O)Cc1ccc(OCC2CC2)c(c1)-c1ccc(F)c2CCN(Cc12)C(=O)OCc1ccccc1 Show InChI InChI=1S/C29H28FNO5/c30-26-10-9-22(24-14-21(15-28(32)33)8-11-27(24)35-17-20-6-7-20)25-16-31(13-12-23(25)26)29(34)36-18-19-4-2-1-3-5-19/h1-5,8-11,14,20H,6-7,12-13,15-18H2,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair