BDBM205728 US9255090, 197

SMILES: CCCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)OCc1ccccc1

InChI Key: InChIKey=VTHAHXJMBOQLFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM205728 (US9255090, 197) Show SMILES CCCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)OCc1ccccc1 Show InChI InChI=1S/C28H28FNO5/c1-2-14-34-26-11-8-20(16-27(31)32)15-23(26)21-9-10-25(29)22-12-13-30(17-24(21)22)28(33)35-18-19-6-4-3-5-7-19/h3-11,15H,2,12-14,16-18H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair