BDBM205738 US9255090, 207::US9255090, 208::US9255090, 227
SMILES: CCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)CC1COc2ccccc12
InChI Key: InChIKey=WTRHXRHWRKRHNN-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G protein-coupled receptor 44 (Homo sapiens (Human)) | BDBM205738 (US9255090, 207 | US9255090, 208 | US9255090, 227) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.0 | 25 |
ACTELION PHARMACEUTICALS LTD. US Patent | Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5... | US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G protein-coupled receptor 44 (Homo sapiens (Human)) | BDBM205738 (US9255090, 207 | US9255090, 208 | US9255090, 227) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.0 | 25 |
ACTELION PHARMACEUTICALS LTD. US Patent | Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5... | US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G protein-coupled receptor 44 (Homo sapiens (Human)) | BDBM205738 (US9255090, 207 | US9255090, 208 | US9255090, 227) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.0 | 25 |
ACTELION PHARMACEUTICALS LTD. US Patent | Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5... | US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2 | |||||||||||
More data for this Ligand-Target Pair |