null
SMILES: CC(N1CCN(CC1)c1cc(Oc2cccc3sc(NC(C)=O)nc23)ncn1)c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=NOJXMKSXBYQUOL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM20579 (N-{4-[(6-{4-[(1S)-1-[4-(trifluoromethyl)phenyl]eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen | Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp... | J Med Chem 50: 3528-39 (2007) Article DOI: 10.1021/jm070191h BindingDB Entry DOI: 10.7270/Q2MW2FF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat)) | BDBM20579 (N-{4-[(6-{4-[(1S)-1-[4-(trifluoromethyl)phenyl]eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Amgen | Assay Description TRPV1 activities were monitored as a function of cellular uptake of radioactive calcium (45Ca2+). The test compounds were preincubated with TRPV1 exp... | J Med Chem 50: 3528-39 (2007) Article DOI: 10.1021/jm070191h BindingDB Entry DOI: 10.7270/Q2MW2FF4 | |||||||||||
More data for this Ligand-Target Pair |