BDBM205861 US9255090, 330

SMILES: CCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)C1CC1c1ccccn1

InChI Key: InChIKey=ZOUMCLPVHMYQKI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM205861 (US9255090, 330) Show SMILES CCOc1ccc(CC(O)=O)cc1-c1ccc(F)c2CCN(Cc12)C(=O)C1CC1c1ccccn1 Show InChI InChI=1S/C28H27FN2O4/c1-2-35-26-9-6-17(14-27(32)33)13-21(26)18-7-8-24(29)19-10-12-31(16-23(18)19)28(34)22-15-20(22)25-5-3-4-11-30-25/h3-9,11,13,20,22H,2,10,12,14-16H2,1H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.0	25
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...				US Patent US9255090 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60B2
					More data for this Ligand-Target Pair