null

SMILES: CC(C)N1CCN(CC1)c1ccc(cc1)C1N(CCc2cc(O)ccc12)c1cccc(O)c1

InChI Key: InChIKey=YLNWZYQQSWHFOP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM20619 (2-(3-hydroxyphenyl)-1-{4-[4-(propan-2-yl)piperazin...) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)C1N(CCc2cc(O)ccc12)c1cccc(O)c1 Show InChI InChI=1S/C28H33N3O2/c1-20(2)29-14-16-30(17-15-29)23-8-6-21(7-9-23)28-27-11-10-26(33)18-22(27)12-13-31(28)24-4-3-5-25(32)19-24/h3-11,18-20,28,32-33H,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	943	n/a	286	n/a	n/a	n/a	25
Novartis Pharmaceuticals					Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...				J Med Chem 48: 364-79 (2005) Article DOI: 10.1021/jm040858p BindingDB Entry DOI: 10.7270/Q2CC0XZJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM20619 (2-(3-hydroxyphenyl)-1-{4-[4-(propan-2-yl)piperazin...) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)C1N(CCc2cc(O)ccc12)c1cccc(O)c1 Show InChI InChI=1S/C28H33N3O2/c1-20(2)29-14-16-30(17-15-29)23-8-6-21(7-9-23)28-27-11-10-26(33)18-22(27)12-13-31(28)24-4-3-5-25(32)19-24/h3-11,18-20,28,32-33H,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	18	n/a	n/a	7.4	22
Novartis Pharmaceuticals					Assay Description Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...				J Med Chem 48: 364-79 (2005) Article DOI: 10.1021/jm040858p BindingDB Entry DOI: 10.7270/Q2CC0XZJ
					More data for this Ligand-Target Pair