BDBM206277 (S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenethylamino)propan-2-yl)-N4-hydroxyterephthalamide (12c)

SMILES: ONC(=O)c1ccc(cc1)C(=O)N[C@H](C(=O)NCCc1ccccc1)c1c[nH]c2ccccc12

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetylases (HDACs) (Homo sapiens (Human))	BDBM206277 ((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenethylamino)...) Show SMILES ONC(=O)c1ccc(cc1)C(=O)N[C@H](C(=O)NCCc1ccccc1)c1c[nH]c2ccccc12 |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	301	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University					Assay Description In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...				Chem Biol Drug Des 89: 38-46 (2017) Article DOI: 10.1111/cbdd.12819 BindingDB Entry DOI: 10.7270/Q2SQ8Z69
					More data for this Ligand-Target Pair