BDBM206282 (S)-N1-(3-(1H-indol-3-yl)-1-((3-methoxyphenyl)amino)-1-oxopropan-2-yl)-N4-hydroxyterephthalamide (12h)

SMILES: COc1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)C(=O)NO)c2c[nH]c3ccccc23)c1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetylases (HDACs) (Homo sapiens (Human))	BDBM206282 ((S)-N1-(3-(1H-indol-3-yl)-1-((3-methoxyphenyl)amin...) Show SMILES COc1cccc(NC(=O)[C@@H](NC(=O)c2ccc(cc2)C(=O)NO)c2c[nH]c3ccccc23)c1 |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	435	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University					Assay Description In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...				Chem Biol Drug Des 89: 38-46 (2017) Article DOI: 10.1111/cbdd.12819 BindingDB Entry DOI: 10.7270/Q2SQ8Z69
					More data for this Ligand-Target Pair