BDBM206345 US9260410, 3

SMILES: CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1

InChI Key: InChIKey=MPFNOCFGLHYSEQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 206345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM206345 (US9260410, 3) Show SMILES CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1 Show InChI InChI=1S/C32H32N6O3/c1-20-10-12-22(13-11-20)38-30(19-28(37-38)32(3,4)5)36-31(40)35-26-14-15-27(25-9-7-6-8-24(25)26)41-23-16-17-33-29(18-23)34-21(2)39/h6-19H,1-5H3,(H,33,34,39)(H2,35,36,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Ltd. US Patent					Assay Description The enzyme inhibitory activities of compounds disclosed herein were determined by fluorescence resonance energy transfer (FRET) using synthetic pepti...				US Patent US9260410 (2016) BindingDB Entry DOI: 10.7270/Q2513X2Q
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM206345 (US9260410, 3) Show SMILES CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1 Show InChI InChI=1S/C32H32N6O3/c1-20-10-12-22(13-11-20)38-30(19-28(37-38)32(3,4)5)36-31(40)35-26-14-15-27(25-9-7-6-8-24(25)26)41-23-16-17-33-29(18-23)34-21(2)39/h6-19H,1-5H3,(H,33,34,39)(H2,35,36,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<18	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Ltd. US Patent					Assay Description The enzyme inhibitory activities of compounds disclosed herein were determined by fluorescence resonance energy transfer (FRET) using synthetic pepti...				US Patent US9260410 (2016) BindingDB Entry DOI: 10.7270/Q2513X2Q
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 12 (Homo sapiens (Human))	BDBM206345 (US9260410, 3) Show SMILES CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3-c3ccc(C)cc3)C(C)(C)C)c3ccccc23)ccn1 Show InChI InChI=1S/C32H32N6O3/c1-20-10-12-22(13-11-20)38-30(19-28(37-38)32(3,4)5)36-31(40)35-26-14-15-27(25-9-7-6-8-24(25)26)41-23-16-17-33-29(18-23)34-21(2)39/h6-19H,1-5H3,(H,33,34,39)(H2,35,36,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
Respivert Ltd. US Patent					Assay Description The enzyme inhibitory activities of compounds disclosed herein were determined by fluorescence resonance energy transfer (FRET) using synthetic pepti...				US Patent US9260410 (2016) BindingDB Entry DOI: 10.7270/Q2513X2Q
					More data for this Ligand-Target Pair