BDBM20641 methyl 4-[(5-carbamoyl-2-methylphenyl)amino]-5-methylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analogue, 3c

SMILES: COC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(N)=O)c2c1C

InChI Key: InChIKey=ZDGDOXAQILZWIJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM20641 (methyl 4-[(5-carbamoyl-2-methylphenyl)amino]-5-met...) Show SMILES COC(=O)c1cn2ncnc(Nc3cc(ccc3C)C(N)=O)c2c1C Show InChI InChI=1S/C17H17N5O3/c1-9-4-5-11(15(18)23)6-13(9)21-16-14-10(2)12(17(24)25-3)7-22(14)20-8-19-16/h4-8H,1-3H3,(H2,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	>2.00E+3	n/a	n/a	7.5	22
Novartis Pharmaceuticals					Assay Description The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...				J Med Chem 51: 4-16 (2008) Article DOI: 10.1021/jm7009414 BindingDB Entry DOI: 10.7270/Q23T9FHB
					More data for this Ligand-Target Pair