BDBM206442 US9260425, 187

SMILES: C1CNCCN(C1)c1cccc(n1)-c1n[nH]c2cnc(cc12)-c1cccnc1

InChI Key: InChIKey=PUECOGCCEUXMDA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM206442 (US9260425, 187) Show SMILES C1CNCCN(C1)c1cccc(n1)-c1n[nH]c2cnc(cc12)-c1cccnc1 Show InChI InChI=1S/C21H21N7/c1-5-17(25-20(6-1)28-10-3-8-22-9-11-28)21-16-12-18(15-4-2-7-23-13-15)24-14-19(16)26-27-21/h1-2,4-7,12-14,22H,3,8-11H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0150	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Genetech, Inc. US Patent					Assay Description PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....				US Patent US9260425 (2016) BindingDB Entry DOI: 10.7270/Q2RR1X3X
					More data for this Ligand-Target Pair