BDBM206495 US9260425, 245::US9260425, 340
SMILES: N[C@H]1CCC[C@H](C1)Nc1cccc(n1)-c1n[nH]c2cnc(cc12)-c1cccnc1
InChI Key:
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM206495 (US9260425, 245 | US9260425, 340) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.00790 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genetech, Inc. US Patent | Assay Description PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J.... | US Patent US9260425 (2016) BindingDB Entry DOI: 10.7270/Q2RR1X3X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM206495 (US9260425, 245 | US9260425, 340) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0440 | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | n/a |
Genetech, Inc. US Patent | Assay Description PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J.... | US Patent US9260425 (2016) BindingDB Entry DOI: 10.7270/Q2RR1X3X | |||||||||||
More data for this Ligand-Target Pair |