BDBM207036 US9260439, 13

SMILES: Nc1ncc(cn1)-c1nc(nc2N(CCc12)C1CC(F)(F)C1)N1CCOCC1

InChI Key: InChIKey=YBCUMMIESLBSNQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207036 (US9260439, 13) Show SMILES Nc1ncc(cn1)-c1nc(nc2N(CCc12)C1CC(F)(F)C1)N1CCOCC1 Show InChI InChI=1S/C18H21F2N7O/c19-18(20)7-12(8-18)27-2-1-13-14(11-9-22-16(21)23-10-11)24-17(25-15(13)27)26-3-5-28-6-4-26/h9-10,12H,1-8H2,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207036 (US9260439, 13) Show SMILES Nc1ncc(cn1)-c1nc(nc2N(CCc12)C1CC(F)(F)C1)N1CCOCC1 Show InChI InChI=1S/C18H21F2N7O/c19-18(20)7-12(8-18)27-2-1-13-14(11-9-22-16(21)23-10-11)24-17(25-15(13)27)26-3-5-28-6-4-26/h9-10,12H,1-8H2,(H2,21,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.307	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair