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BDBM207063 US9260439, 40

SMILES: CO[C@H]1C[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=UIHBTAMDSVFZMF-HDJSIYSDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207063   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
p110α/p85α


(Homo sapiens (Human))		BDBM207063
PNG
(US9260439, 40)
Show SMILES CO[C@H]1C[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1 |r,wU:4.6,wD:2.1,(4.61,-7.42,;5.38,-6.08,;4.61,-4.75,;5.01,-3.26,;3.52,-2.86,;3.12,-4.35,;2.75,-1.53,;3.66,-.28,;2.75,.96,;1.29,.49,;1.29,-1.05,;-.05,-1.82,;-1.38,-1.05,;-1.38,.49,;-.05,1.26,;-.05,2.8,;1.29,3.57,;1.29,5.11,;-.05,5.88,;-.05,7.42,;-1.38,5.11,;-1.38,3.57,;-2.71,-1.82,;-4.05,-1.05,;-5.38,-1.82,;-5.38,-3.36,;-4.05,-4.13,;-2.71,-3.36,)|
Show InChI InChI=1S/C19H25N7O2/c1-27-14-8-13(9-14)26-3-2-15-16(12-10-21-18(20)22-11-12)23-19(24-17(15)26)25-4-6-28-7-5-25/h10-11,13-14H,2-9H2,1H3,(H2,20,21,22)/t13-,14-
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 0.416n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...

US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair