BDBM207140 US9260439, 117

SMILES: CNS(=O)(=O)N1C[C@@H](OC)[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C

InChI Key: InChIKey=IIILFJZWUSDOMV-IAOVAPTHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p110alpha-iSH2 p85alpha Complex (Homo sapiens (Human))	BDBM207140 (US9260439, 117) Show SMILES CNS(=O)(=O)N1C[C@@H](OC)[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C21H31N9O4S/c1-13-12-34-7-6-29(13)21-26-18(14-8-24-20(22)25-9-14)15-4-5-30(19(15)27-21)16-10-28(11-17(16)33-3)35(31,32)23-2/h8-9,13,16-17,23H,4-7,10-12H2,1-3H3,(H2,22,24,25)/t13-,16+,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.179	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM207140 (US9260439, 117) Show SMILES CNS(=O)(=O)N1C[C@@H](OC)[C@@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOC[C@@H]1C |r| Show InChI InChI=1S/C21H31N9O4S/c1-13-12-34-7-6-29(13)21-26-18(14-8-24-20(22)25-9-14)15-4-5-30(19(15)27-21)16-10-28(11-17(16)33-3)35(31,32)23-2/h8-9,13,16-17,23H,4-7,10-12H2,1-3H3,(H2,22,24,25)/t13-,16+,17+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER INC. US Patent					Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D...				US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV
					More data for this Ligand-Target Pair