BDBM207153 US9260439, 130
SMILES: CNS(=O)(=O)[C@H]1CC[C@H](C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
InChI Key: InChIKey=KVEBWLGXMFIWSD-CABCVRRESA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
p110α/p85α (Homo sapiens (Human)) | BDBM207153 (US9260439, 130) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.352 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
PFIZER INC. US Patent | Assay Description PI3KA_FL: Genes encoding for full length p110alpha and p85alpha subunits of PI3Kalpha complex were subcloned from existing constructs into pFASTBAC D... | US Patent US9260439 (2016) BindingDB Entry DOI: 10.7270/Q2VH5MPV | |||||||||||
More data for this Ligand-Target Pair |