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BDBM207439 US9260439, 323

SMILES: C[C@@]1(CCN(C1)C(=O)CC1CC1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=ZGHOIZOORPWYIK-DEOSSOPVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207439   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
p110alpha-iSH2 p85alpha Complex


(Homo sapiens (Human))		BDBM207439
PNG
(US9260439, 323)
Show SMILES C[C@@]1(CCN(C1)C(=O)CC1CC1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
Show InChI InChI=1S/C24H32N8O2/c1-24(5-7-31(15-24)19(33)12-16-2-3-16)32-6-4-18-20(17-13-26-22(25)27-14-17)28-23(29-21(18)32)30-8-10-34-11-9-30/h13-14,16H,2-12,15H2,1H3,(H2,25,26,27)/t24-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
<0.0180n/an/an/an/an/an/an/an/a



PFIZER INC.

US Patent


Assay Description
PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...

US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair